A hormone-free blend to relieve the symptoms of menopause, day and night.†
Why use a natural menopause formula? Symptom relief†:
The right formula can be a natural way to deal with hot flashes, night sweats and mood swings.†
Better sleep & energy†:
Using a nighttime herbal formula can support menopausal symptom relief and restful sleep.†
Why use AM/PM Menopause Formula™†? 24-hr Hormone-Free symptom relief!†
Time-tested, standardized black cohosh provides 24-hour natural hormonal support and relief from hot flashes, night sweats, mood swings and irritability.†
Energy for the day†:
The AM Formula contains Panax ginseng and green tea to provide daytime energy and support breast health.†
Better sleep at night†:
The PM Formula gives you the natural sleep support of L-Theanine and valerian with no morning grogginess.†
Note: The black cohosh is wild crafted in the United States.1
Menopause PM:
It is estimated that over 5,400 women enter menopause daily in North America.3 For most women, menopause occurs as part of the natural aging process, usually between the ages of 35 and 58.2 This hormonal change is influenced by many factors, including genetics, diet, lifestyle, and environmental stresses.3-6 “Premature” menopause is sometimes linked to other physical or hormonal disorders.5 Some women may experience “induced” menopause as a result of surgical removal of the ovaries.2,5
Menopause is not a disease, but a natural event signaling the end of fertility. Menopause-related changes are unique for each woman and may range from mild to severe. In early menopause, some women may experience mood swings, panic attacks, sleep disturbances, depression, changes in tolerance to heat or cold, joint and muscle pain, allergies, and headaches. As production of estrogen decreases, additional menopause-related changes may include irregular menstrual patterns, night sweats, fatigue, vaginal dryness, fluctuations in sexual desire or response, forgetfulness, hot flashes, and weight fluctuations.3-5
The most common menopausal disturbance is the "hot flash" (or "hot flush") - a sudden warm feeling in the face and/or upper body, accompanied by blushing, increased pulse rate, and sometimes perspiration. A cold chill often follows. A few women have only the chill without the flash. The hot flash results from a change in the body's circulation. The usual underlying cause is decreasing or fluctuating estrogen levels.3
Hot flashes that occur with drenching perspiration while sleeping are called "night sweats." Night sweats and hot flashes may interfere with sleep. Falling estrogen levels alone can also disrupt patterns of healthy deep sleep. Without adequate sleep that progresses undisturbed through all the sleep stages, women can become tired and irritable. Therefore, fatigue and irritability are considered secondary symptoms that may be alleviated by addressing the underlying cause, which is lack of sleep.3
Among the many misconceptions associated with menopause is that mental health problems, such as depression and anxiety, are inevitable as hormone production decreases. In reality, there are no scientific studies to support the belief that natural menopause is responsible for true clinical depression, clinical anxiety, severe memory lapses, or erratic behavior. However, women who have been deprived of sleep because of menopausal night sweats and changes in estrogen levels can feel tired, irritable, and moody. Additionally, the hormone fluctuations, although normal, can be stress provoking, which creates emotional upsets, mood changes, and intermittent anxiety.3
Due to the diversity of symptoms related to menopause, a broad-spectrum menopause formula must address hot flashes, improve sleep quality, increase resistance to stress, reduce fatigue, and promote relaxation. The following herbs were chosen for their ability to relieve menopausal symptoms.
Black Cohosh and menopause Black cohosh (Cimicifuga racemosa) has traditionally been used for relief of menopausal complaints, especially hot flashes.† Although the exact mechanism of its action has not been fully elucidated, the strongest evidence for the use of black cohosh comes from the results of clinical trials. A series of open clinical studies in more than 800 subjects demonstrated good efficacy of black cohosh extract in relieving hot flashes.† Several double blind, placebo-controlled studies also demonstrate that black cohosh extract is beneficial in relieving menopausal symptoms.†7-8
The German Commission E monograph for black cohosh does not recommend its use for longer than 6 months, because of the lack of long-term safety data. However, to date, no evidence of toxicity or serious side effects has ever been reported in women.9,10
The primary constituents in Cimicifuga racemosa extract are glycosides, specifically triterpene glycosides that include cimicifugoside, actein, and 27-deoxyactein. The Cimicifuga racemosa extracts used in AM/PM Menopause Formula† are standardized to these triterpene glycosides measured as 27-deoxyactein.9,11,12
Early research hypothesized that black cohosh exerted estrogen-like effects.11 Recent laboratory research shows that black cohosh binds to the estrogen receptor; however, it does not affect the luteinizing hormone level and does not exhibit estrogen-like effects.13 Thus, there is currently no consensus as to the biological effect of this binding.9,12-15 In small, as-yet unpublished human studies, there is indication that Cimicifuga racemosa does not alter estrogen levels and does not change the thickness of the lining of the uterus.14
The question of how black cohosh works at the cellular level is currently being addressed in several ongoing research projects.15 To date, there is no definitive published data available to clearly describe the process; however, forty years of clinical studies on a standardized black cohosh extract show efficacy in the relief of hot flashes, profuse sweating, occasional sleeplessness, and support of mood.†10,16
Clinical Trials on Black Cohosh A randomized, placebo-controlled, double-blind study compared women who took standardized black cohosh extract with women taking conjugated estrogen or a placebo. At the end of the study, the women taking the standardized black cohosh extract showed improvement relative to the placebo as measured by the Kupperman Menopausal Index, the Hamilton Anxiety Scale, and the maturation index of vaginal epithelium.† No clear improvement of menopausal complaints was observed in the control group. This study demonstrated clinical and statistical improvement of symptoms by the women taking the standardized black cohosh extract.†7,17
AM Formula
Ginseng Ginseng has an ancient reputation as a tonic. In folk medicine, ginseng has been ascribed “masculine” properties; however, ginseng has been used by both men and women for a variety of applications. The Complete German Commission E Monograph has approved ginseng to combat fatigue and weakness, as a restorative for declining stamina and impaired concentration, and as an aid to convalescence.18 A double-blind, placebo-controlled study with 384 symptomatic postmenopausal women showed a tendency towards slightly better overall symptom relief, and a significant improvement in mood and well-being after supplementation of ginseng extract for 16 weeks.†19
A recent study of postmenopausal women with menopausal syndromes reported that when Korean red ginseng was used for 30 days, Cornell Medical Index (CMI) and State-Trait Anxiety Inventory (STAI) score was decreased with significant improvement in fatigue, poor sleep quality, and depression.†20 Therefore, Panax ginseng appears to be useful for relieving menopausal complaints.†21
Green Tea Green tea is a dried product of the fresh shoot of the tea plant (Camellia sinensis) from which numerous biological activities have been reported.21 One component is caffeine. Caffeine has been extensively studied as an ergogenic (energy producing) aid. It has shown consistent ergogenic effects for the support of overall health, stamina, and the reduction of fatigue.†21
The green tea leaf extract in this product is standardized to contain 14% caffeine. Therefore, the green tea leaf extract delivers 35 mg of caffeine. One cup (7 ounces) of drip coffee provides 115-175 mg caffeine.23 The North American Menopause Society recommends moderation, not necessarily elimination, of caffeine intake (which could be 1-2 cups of coffee per day) for women experiencing hot flashes.3 The amount of caffeine in this product is less than 1/3 to 1/5 a cup of coffee.
Many researchers in the field of women's health suggest moderation in the intake of spicy foods, hot drinks, caffeine and alcohol as effective ways to alleviate hot flashes.3,24 Given the small amount of caffeine (35 mg) in this product, and the fact that green tea is in the AM formula, it seems reasonable that the positive ergogenic effects and healthy benefits of green tea supplementation outweigh the potential negative effects of caffeine.
Additionally, a 1998 study indicates that green tea supports women's breast health in a variety of ways.†22 Green tea is a rich source of flavonoids and polyphenols, namely, catechins and flavonols. The catechins, also known as tea polyphenols, which occur in significant quantities in green tea, are catechin, epicatechin, gallocatechin, epigallocatechin, epicatechin gallate, and epigallocatechin gallate (EGCG). A study has indicated that EGCG supports healthy breast cell development.†25
PM formula: The ingredients in the PM tablet of AM/PM Menopause Formula† are included to promote relaxation and sleep.† Poor sleep quality can lead to medical, psychological, and social disturbances. Conventional medical treatment for sleep problems includes psychological and pharmacological approaches. 26
However, use of frequently prescribed sleep or sedative medications can lead to dependency and cause unwanted side effects or problematic withdrawal symptoms. The following herbs, commonly used for their relaxing or sedative properties, do not demonstrate side effects such as tolerance, habituation, and addiction.26,27
Valerian Valerian (Valeriana officinalis) has been reported to have sleep inducing and calming effects in in-vivo studies and clinical trials.† A placebo-controlled, crossover trial of 128 volunteers reported 400 mg of valerian extract at bedtime led to improved sleep quality, decreased sleep latency, and reduced the number of night awakenings.† Two other clinical studies using 400-900 mg valerian before bedtime also demonstrated improved sleep quality.† In a double-blind, cross-over, placebo-controlled trial, subjective sleep latency and wake time after sleep-onset were reduced by more than half after a 900 mg dose, with a smaller effect after 450 mg.† One electroencephalographical (EEG) study reported 135 mg of aqueous, dried extract of valerian, taken three times daily, improved delta sleep and decreased stage 1 sleep.†26-32
Recently, two human trials also demonstrated that valerian extract was effective in improvement of sleep structure and perception in subjects.†33,34 In general, clinical studies with valerian extracts suggest that the mild sleep-inducing effect of valerian decreases sleeps latency and improves sleep quality.†32
L-Theanine L-theanine is one of the major components of amino acids in green tea. However, L-theanine does not contain any caffeine, even though it is from green tea.
L-theanine's effect on brain amino acids and neurotransmittors has been investigated. In clinical trials, L-theanine causes significant increases of certain neurotransmitter concentrations in brain, which promotes muscle relaxation and improves sleep.†35,36
Hops The dried strobile of Hops (Humulus lupulus) is a popular sleep aid. Hops have been used for centuries for gastrointestinal health support, and have more recently been used to support healthy sleep.† Key constituents of hops include a volatile oil, valerianic acid, phytoestrogenic substances, tannins, and flavonoids. Hops have been demonstrated to induce sleep.†26,37
Suntheanine®, a patented form of L-Theanine, is a trademark of Taiyo International, Inc.
Vegetarian
ETI is an FDA-registered Drug Establishment.
This product has a tamper-evident foil pouch. Do not use if foil or plastic is punctured!
**Based on 2000 calorie diet.Other Ingredients: Both Formulas: cellulose, modified cellulose gum, modified cellulose, stearic acid, magnesium stearate, titanium dioxide color, silicon dioxide, soy lecithin, vegetable glycerin, carrot color, paprika extract color, and carnauba wax.UPC Codes: 763948072064
How do I know which formula (AM/PM PeriMenopause Formula™† or AM/PM Menopause Formula™†) is best for me?
Your age and the symptoms you are experiencing can help you determine which AM/PM Formula is best for you. While most women between the ages of 35 and 45 are not in menopause (they’re still menstruating) something is definitely going on hormonally and it may show up in several distressing symptoms, including:
These symptoms all point to perimenopause, a period in women’s lives defined by fluctuating hormones. The answer to these symptoms is AM/PM Perimenopause Formula, containing black cohosh, green tea, chaste tree berry, and Rhodiola in the morning tablet, and black cohosh, valerian, and hops for proven evening symptom reduction.†
Most women enter menopause when they reach their mid to late forties or early fifties. As menopause signals the end of a woman’s fertility, her ovaries slowly stop producing estrogen and progesterone, her periods become less frequent and more irregular, and finally stop about 3 to 5 years later. Women in menopause may experience intense hot flashes, wild mood swings, and disruptive night sweats. And they often feel rundown and fatigued during the day. AM/PM Menopause Formula contains black cohosh, ginseng, and green tea in the morning (AM) tablet and black cohosh, valerian, hops, and the amino acid L-theanine in the tablet taken in the evening.†
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